DMPK Services

Hepregen offers a range of DMPK services using our HepatoPac® co-culture system. Our experienced scientific staff works closely with our clients to design assays to meet their needs. We take great pride in our quality results and impeccable customer care. If you don't see your application of interest, our scientists can work with you to create a custom assay.

Why use Hepregen HepatoPac Technology?

  • Able to conduct low turnover metabolic stability studies because of the extended functionality and sensitivity of HepatoPac co-cultures
  • More predictive than conventional hepatocyte models
  • Highly reproducible, accurate results - HepatoPac is a fully validated micro-liver platform
  • Identify species-specific results - HepatoPac is available for human, rat, monkey and dog models

Working with Hepregen

Your collaboration with Hepregen begins with a study planning exercise. Your Hepregen Account Manager will set up a meeting between you, our scientific team, and a Client Research Specialist to discuss the specific goals of your project. Following the meeting, a Project Manager will be assigned to your project and will work with you to design a custom work-plan. The Project Manager will also work with you to coordinate the shipment and receipt of your test articles. Once the study has been completed,our Senior Scientist will generate a report consisting of background, methods, results (including the raw data), and conclusions. After your receipt of the final report, we will follow up with you to discuss the final results and address any questions. Throughout this process, your Account Manager and Project Manager will be available to you for questions and/or updates.

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Technical Resources

Type Title
Publication Long-Term Stability of Primary Rat Hepatocytes in Micropatterned Co-Cultures. J Biochem Molecular Toxicology, Vol. 27(3), p 204–212,(2013).
Publication Assessment of MicroPatterned Hepatocyte Co-culture System to Generate Metabolites.
Case Study Ability of a Micropatterned Hepatocyte Co-culture System to Generate Major Human Drug Metabolites.

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