Hepregen Presentations and Posters

Presentations

Phenotypic characterization of the micropatterned primary hepatocyte coculture HepatoPac and its use in the in vitro toxicity assessment of the nucleoside analog Fialuridine
Presented by: Dr. Anita Dankers, Janssen
2015 SOT Conference
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Application of a micropatterned co-cultured (MPCC) hepatocyte system to predict preclinical and human specific drug metabolism
Presented by: Dr. Scott Obach, Pfizer
2014 ISSX Conference
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The Use of Human HepatoPac®, an In Vitro Microliver Platform, for Predictive Toxicology
Presented by: Dr. Edward LeCluyse, The Hamner Institutes for Health Sciences
2014 SOT Conference
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HepatoPac® Cultures: Low Clearance and Metabolite Identification Application
Presented by: Caroline Lee, QPS
2013 ISSX Conference
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For access to Hepregen's User Group Meeting presentations, please visit our User Group Meeting page.

 

Posters

Tissue-Engineered Long Term Hepatocyte Co-culture Model And Data Independent Mass Spectrometry Acquisition To Identify Multi Generation Metabolites
Presented by Dr. Suma Ramagiri, SCIEX
2015 ASMS Conference
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In Vitro Modeling of Inflammation-Drug Interactions Using Micropatterned Cocultures of Primary Hepatocytes and Kupffer Macrophages 
Presented by Dr. Onyi Irrechukwu (Hepregen Corporation) at the 2015 SOT Meeting
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Nuclear Receptor-Mediated Changes in Gene Expression in a Human Hepatic Micropatterned Coculture Model following Treatment with Hepatotoxic Compounds
Presented by Dr. Kelly Rose (The Hamner Institutes for Health Sciences) at the 2015 SOT Meeting
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A Novel In Vitro Model to Assess Chemical-Induced Steatosis and Phospholipidosis 
Presented by Dr. Kristina Wolf (The Hamner Institutes for Health Sciences) at the 2015 SOT Meeting
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Differential Effects of FIAU, FIRU, and DDC on Functional and DNA Content Endpoints in HepatoPac and Huh7 Cells 
Presented by Dr. Jose Lebron (Merck Research Laboratories) at the 2015 SOT Meeting
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In Vitro Toxicity Assessment of the Nucleoside Analog Fialuridine Using Micropatterned Primary Hepatocyte Cocultures and Discovery of a Nontoxic Isomer 
Presented by Dr. Anita Dankers (Janssen) at the 2015 SOT Meeting
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Multiplexed Method to Screen for Chemical-Induced Hepatotoxicity using a Novel Micropatterned Human Hepatocyte Co-Culture Platform
Presented by Dr. Edward LeCluyse (The Hamner Institutes for Health Sciences) at the 2015 SOT Meeting
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Phenotypic Assessment of Toxicity Using a Human Hepatocyte Co-Culture Model
Presented by Jayne Hesley (Molecular Devices) at 2015 Cambridge Healthtech HCA Conference
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Metabolism of Eight Model Pharmaceutical Compounds in Rat and Human HepatoPac Versus Liver Microsomes and Suspension Hepatocyte Platforms
Presented by Julianne Jing Shi at 2014 ISSX Conference
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Toxicity of Selected Bioactivated Compounds in Primary Rat Hepatocytes Cultured in Micropatterned Co-Cultures
Presented by Okey Ukairo at 2014 Eurotox Conference
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In Vitro Species Comparison Using Long-Term Hepatocyte Co-Cultures Model and Highly Sensitive UHPLC-QTOF-MS with SWATH Analysis.
Presented by QPS at 2014 ASMS Conference
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Metabolite Profiling Using Human Hepatocyte Co-cultures and UHPLC-QTOF-MS with Data Independent MS/MS.
Presented by QPS at 2014 ASMS Conference
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Metabolic Stability Assay Using Human Hepatocyte Co-cultures and Integrated Qualitative/Quantitative High Resolution Mass Spectrometry.
Presented by QPS at 2014 ASMS Conference
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Comparative Metabolism of Eight Model Pharmaceutical Compounds in Rat and Human Liver Microsomes, Suspension Hepatocytes and Micropatterned Co-cultures of Primary Hepatocytes.
Presented in conjunction with Ricerca at 2014 SOT
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Evaluation of the Toxicity Profiles of Selected Bioactivated Compounds in Primary Rat Hepatocytes Cultured in Micropatterned Cocultures.
Presented at 2014 SOT Conference
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A Micropatterned Culture with Primary Hepatocytes and Kupffer Macrophages for Studying Inflammation-Drug Interactions.
Presented at the 2013 AAPS Conference
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Bioactivation and Toxcicity of Acetaminophen in Rat Primary Hepatocytes Cultured in Micropatterned Co-cultures.
Presented at the 2013 ISSX Conference
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Modeling of Cytokine-Drug Interactions Using Micropatterned Co-Cultures of Primary Hepatocytes and Kupffer Macrophages.
Presented at the 2013 EuroTox Conference
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A Micropatterned Culture with Primary Hepatocytes and Kupffer Macrophages for Studying Inflammation-Drug Interactions.
Presented at the 2012 ISSX Conference
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Global Gene Expression Changes Induced In Primary Human Hepatocytes by Thiazolidinediones Upon Repeat Dosing of HepatoPac® Cultures
Presented at 2011 ISSX Conference
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Be Careful What You Ask For: Challenges of Predicting Human Clearance for a Low Metabolic Turnover Compound
Presented in collaboration with Elan Pharmaceuticals at the 2011 ISSX Conference
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HepatoPac® Allows Determination of Toxicity under Chronic Dosing and at Relevant Concentrations
Presented at the 2011 Society of Toxicology Conference
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Micropatterned Primary Hepatocyte Co-Cultures for Drug Metabolism and Toxicity Studies
Presented at the 2011 Society of Toxicology Conference
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Enhancement of Proliferation in a Novel Rat Hepatocyte Co-Culture Model after Mitogenic Stimulation.
Presented in collaboration with the US EPA at the 2012 Society of Toxicology Conference
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Assessment of a Micropatterned Hepatocyte Co-Culture System to Detect Compounds that Cause Drug Induced Liver Injury in Humans.
Presented in collaboration with Pfizer at the 2012 Society of Toxicology Conference
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